Upsloping ST depression can be associated with myocardial ischemia, but less often than horizontal or downsloping ST depression.
See also: ST segment
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This ECG is from an elderly woman who presented with altered mental status on a hot summer day.
This ECG shows sinus tachycardia (124), ST elevation in V1-2 and III and upsloping ST depression in I, aVL and V4-6. POCUS did not show a regional wall motion abnormality. The ST changes resolved with active cooling.